Ad26.COV2.S (Johnson & Johnson)
Ad26.COV2.S (Johnson & Johnson)

Ad26.COV2.S (Johnson & Johnson)

To create the Ad26.COV2.S vaccine, the tried-and-true Ad26 adenovirus vector was used. In the past, Johnson & Johnson employees used it to create vaccines against Ebola and other infections.
Janssen

Janssen

Ad26.COV2.S (also known as COVID-19 Janssen, JNJ-78436735 or Ad26COVS1) is a vaccine against SARS-CoV-2 from Janssen-Cilag International NV (Janssen Pharmaceutica), located in Beerse (Belgium) and part of the Johnson & Johnson international healthcare corporation. The vaccine contains genetic data for the biosynthesis of SARS-COV-2 spike protein. The adenovirus serves as a vector (transport mechanism) for the genetic data needed to synthesize this protein. Afterwards, the spike proteins synthesized by the vaccinated person induce an immune reaction that prepares the immune system for subsequent SARS-CoV-2 infection.

Vaccine

Ad26.COV2.S

Developer

Johnson & Johnson

Производитель

Johnson & Johnson

Status

Over the course of clinical trials by 44,000 volunteers from the United States, South Africa and Latin American countries, the vaccine demonstrated a 67% effectiveness rate.
The third phase of trials, which began in September 2020, will include 45,000 volunteers, with results expected by January. In November 2020, the company announced additional trials to evaluate the potential benefits of a second dose of the vaccine. After approval, total production of the vaccine is estimated to reach 1 billion doses per year, with worldwide availability.

Key information

What’s in the vaccine?

To create the Ad26.COV2.S vaccine, the tried-and-true Ad26 adenovirus vector was used. In the past, Johnson & Johnson employees used it to create vaccines against Ebola and other infections.